ARCTURUS THERAPEUTICS HOLDINGS INC (ARCT)

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2026 Annual Meeting Analysis

ARCTURUS THERAPEUTICS HOLDINGS INC · Meeting: June 5, 2026

Policy v1.2high confidenceView Filing ↗
For informational purposes only. This AI-generated analysis applies a published voting policy to publicly available proxy filings. It does not constitute investment advice, proxy voting advice, or a solicitation of any kind. AI analysis may be incomplete or inaccurate — always review the actual filing and make your own independent decision.

Directors FOR

1

Directors AGAINST

7

Say on Pay

FOR

Auditor

FOR

Director Elections

Election of Directors

1 FOR/7 AGAINST

Against Analysis

✗ AGAINST
Dr. Peter FarrellTSR trigger fired: ARCT 3-year return -68.0% vs XBI 3-year return +67.5%, gap of -135.5pp exceeds 30pp threshold for negative absolute TSR5-year TSR mitigant does not apply: 5-year return -77.7% represents sustained underperformanceDirector since May 2018, tenure fully overlaps underperformance period

Dr. Farrell has served since May 2018 and his tenure fully overlaps the severe underperformance period during which ARCT fell 68% while the XBI — SPDR S&P Biotech ETF — rose 67.5%, a gap of 135.5 percentage points far exceeding the 30-point trigger threshold, and the 5-year return of -77.7% confirms this is sustained underperformance rather than a temporary dip.

✗ AGAINST
Joseph E. PayneTSR trigger fired: ARCT 3-year return -68.0% vs XBI 3-year return +67.5%, gap of -135.5pp exceeds 30pp threshold for negative absolute TSR5-year TSR mitigant does not apply: 5-year return -77.7% represents sustained underperformanceDirector and CEO since March 2013, tenure fully overlaps underperformance periodExecutive director subject to same TSR trigger independent of Say on Pay vote

Mr. Payne has served as CEO and director since March 2013, giving him the longest tenure and deepest accountability for the period during which ARCT lost 68% of its value while the XBI — SPDR S&P Biotech ETF — gained 67.5%, a gap of 135.5 percentage points; the 5-year return of -77.7% confirms prolonged value destruction, and as the company's chief executive he bears the greatest responsibility for this outcome.

✗ AGAINST
James BarlowTSR trigger fired: ARCT 3-year return -68.0% vs XBI 3-year return +67.5%, gap of -135.5pp exceeds 30pp threshold for negative absolute TSR5-year TSR mitigant does not apply: 5-year return -77.7% represents sustained underperformanceDirector since May 2018, tenure fully overlaps underperformance period

Mr. Barlow has served since May 2018 and his entire tenure overlaps the severe underperformance period; ARCT's stock fell 68% over three years while the XBI — SPDR S&P Biotech ETF — rose 67.5%, a 135.5-point gap well above the 30-point trigger, and the 5-year record of -77.7% shows this is not a temporary issue.

✗ AGAINST
Dr. Edward W. HolmesTSR trigger fired: ARCT 3-year return -68.0% vs XBI 3-year return +67.5%, gap of -135.5pp exceeds 30pp threshold for negative absolute TSR5-year TSR mitigant does not apply: 5-year return -77.7% represents sustained underperformanceDirector since September 2019, tenure substantially overlaps underperformance period

Dr. Holmes has served since September 2019, meaning his nearly six-year tenure substantially overlaps the underperformance period during which ARCT fell 68% versus a 67.5% gain for the XBI — SPDR S&P Biotech ETF — and the 5-year return of -77.7% confirms persistent underperformance that cannot be attributed to a recent short-term trough.

✗ AGAINST
Dr. Magda MarquetTSR trigger fired: ARCT 3-year return -68.0% vs XBI 3-year return +67.5%, gap of -135.5pp exceeds 30pp threshold for negative absolute TSR5-year TSR mitigant does not apply: 5-year return -77.7% represents sustained underperformanceDirector since May 2018, tenure fully overlaps underperformance period

Dr. Marquet has served since May 2018, and her full tenure overlaps the period in which ARCT's stock declined 68% while the XBI — SPDR S&P Biotech ETF — gained 67.5%, a devastating 135.5-point gap; the 5-year return of -77.7% makes clear this is not a transient underperformance.

✗ AGAINST
Dr. Jing L. MarantzTSR trigger fired: ARCT 3-year return -68.0% vs XBI 3-year return +67.5%, gap of -135.5pp exceeds 30pp threshold for negative absolute TSR5-year TSR mitigant does not apply: 5-year return -77.7% represents sustained underperformanceDirector since December 2021, tenure exceeds 24-month exemption and substantially overlaps underperformance period

Dr. Marantz joined in December 2021 — more than 24 months before this meeting — so she does not qualify for the new-director exemption; her tenure overlaps the three-year period in which ARCT fell 68% against a 67.5% gain for the XBI — SPDR S&P Biotech ETF — and shareholders have experienced sustained losses over five years as well.

✗ AGAINST
Dr. John H. MarkelsTSR trigger fired: ARCT 3-year return -68.0% vs XBI 3-year return +67.5%, gap of -135.5pp exceeds 30pp threshold for negative absolute TSR5-year TSR mitigant does not apply: 5-year return -77.7% represents sustained underperformanceDirector since December 2022, tenure exceeds 24-month exemption and overlaps the majority of the underperformance period

Dr. Markels joined in December 2022, which is more than 24 months before this meeting, so the new-director exemption does not apply; he has been a director during the bulk of the three-year window in which ARCT fell 68% while the XBI — SPDR S&P Biotech ETF — rose 67.5%, and the 5-year trajectory of -77.7% confirms sustained destruction of shareholder value.

For Analysis

✓ FOR
Dr. Moncef Slaoui

Dr. Slaoui joined the board in June 2024, which is less than 24 months before this meeting, so he qualifies for the new-director exemption under the policy and cannot be held accountable for the underperformance that predates his arrival; his extensive vaccine industry credentials at GlaxoSmithKline and Operation Warp Speed provide relevant expertise for a biotechnology company.

Seven of eight director nominees receive an AGAINST vote because the TSR underperformance trigger fires decisively — ARCT's 3-year stock return of -68% trails the XBI — SPDR S&P Biotech ETF — by 135.5 percentage points, far exceeding the 30-point threshold for companies with negative absolute returns, and the 5-year return of -77.7% eliminates any mitigant for sustained performance. Only Dr. Slaoui, who joined in June 2024 and falls within the 24-month new-director exemption, receives a FOR vote.

Say on Pay

✓ FOR

CEO

Joseph E. Payne

Total Comp

$1,691,000

Prior Support

96.9%%

The CEO's total reported compensation of $1,691,000 for 2025 is well within reasonable range for a biotech CEO at a ~$244M market-cap company, and the company explicitly states this figure was below the median of its peer group and 54% lower than the prior year — a direct and appropriate response to a declining stock price. No cash bonuses were paid to any named executive officer for 2025, all equity awards are in the form of stock options that only have value if the stock price increases, and the prior-year Say on Pay vote received 96.9% support indicating broad shareholder satisfaction with the pay program structure. While the stock performance record is deeply concerning and drives Against votes on director elections, the pay level itself is modest and the structure appropriately ties executive rewards to future stock price appreciation.

Auditor Ratification

✓ FOR

Auditor

Deloitte & Touche LLP

Tenure

2 yrs

Audit Fees

$971,000

Non-Audit Fees

$120,000

Deloitte was appointed in April 2024 and has been the auditor for approximately two years, well below the 25-year tenure threshold; non-audit fees of $120,000 (tax fees of $5,000 plus other fees of $115,000) represent about 12.4% of audit fees of $971,000, comfortably below the 50% independence threshold; and Deloitte is a Big Four firm appropriate for a Nasdaq-listed biotech company.

Overall Assessment

The 2026 Arcturus Therapeutics annual meeting ballot presents three standard proposals; the dominant issue is severe and sustained stock underperformance — ARCT has lost 68% over three years and 77.7% over five years while the XBI — SPDR S&P Biotech ETF — gained 67.5% over the same three-year period, triggering Against votes on seven of eight director nominees. The Say on Pay and auditor ratification proposals both pass the policy screens cleanly, with CEO pay modest and below peer median, no cash bonuses paid for 2025, and Deloitte recently appointed with a clean fee structure.

Filing date: April 24, 2026·Policy v1.2·high confidence